Anti-human T-lymphocyte monoclonal antibody
AssigneeThe Board of Trustees of the Leland Stanford Jr. University
InventorsCharles P. Bieber, Frank D. Howard
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Abstract
Mammalian monoclonal antibodies specific for an antigen diagnostic for thymocytes, normal peripheral T cells and some null cells. The antibodies which distinguish among subpopulations of T cells, find use in assays, cell sorting, and immunosupression.
Claims9
Mammalian monoclonal antibodies specific for the lymphocyte antigen Leu-5, specifically binding to thymocytes and E-rosette forming peripheral blood lymphocytes and inhibiting human thymocyte rosette formation.
Mammalian monoclonal antibodies specific for the lymphocyte surface antigen Leu-5 having a label providing a detectible signal, specifically binding to human thymocytes and human peripheral blood lymphocytes which form E-rosettes and inhibiting E-rosette formation of human thymocytes.
Dependencies are inferred from the claim text.