Method for the N-acylation of aminocarboxylic acids
AssigneeDynamit Nobel Aktiengesellschaft
InventorGiselher Franzmann
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Abstract
A process is disclosed for the prparation of an acylated aminocarboxylic acid which comprises contacting an aminocarboxylic acid, its alkali metal or alkaline earth metal salt with a low alkyl carboxylic acid ester of the formula R.sub.1 -CO-O-R.sub.2, wherein R.sub.1 represents hydrogen or a straight-chain or branched or cyclic hydrocarbon moiety of 1 to 30 carbon atoms, which can be substituted if desired, and wherein R.sub.2 represents a straight-chain, branched or cyclic hydrocarbon moiety of 1 to 8 carbon atoms in the presence of an alkali metal or alkaline earth metal alcoholate.
Claims18
A process for the preparation of an ##STR1## acylated 3,4-di-hydroxyphenyl alanine or a naturally occurring aminocarboxylic acid, which comprises the step of contacting its alkali metal or alkaline earth metal salt with a lower alkyl carboxylic acid ester of the formula
- R.sub.1 -CO-O-R.sub.2,
- wherein R.sub.1 represents hydrogen or a straight-chain or branched or cyclic hydrocarbon moiety of 1 to 30 carbon atoms, and wherein R.sub.2 represents a straight-chain, branched or cyclic hydrocarbon moiety of 1 to 8 carbon atoms, in the presence of an alkali metal or alkaline earth metal alcoholate.
Dependencies are inferred from the claim text.