Topical treatment of dry skin
OwnerEugene J. Van Scott, Ruey J. Yuinventors
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Abstract
Preventive as well as therapeutic treatment to alleviate the symptoms of disorders characterized by cracking, flaking, or scaling of the skin consisting of the topical application of a solution, lotion, gel, stick, powder, cream or ointment containing as active ingredients one or more hydroxy acid or its analogue is disclosed. The hydroxyacid and its analogues include free acid, amide, lactone, ester, anhydride, organic or inorganic salt form of hydroxymonocarboxylic acids, hydroxydicarboxylic acids, hydroxytricarboxylic acids and keto acids. The therapeutic composition may include one or more of the compounds present in the total amount of from 0.1 to 20 percent. Topical application to affected areas has been found to ameliorate dry skin conditions.
Claims12
A method for alleviating the symptoms of dry skin in humans comprising topically applying to involved areas of the human body an effective amount of at least one member selected from the group consisting of:
- ______________________________________ Glycolic Acid Malic Acid Glucuronic Acid Mucic Acid Galacturonic Acid Citric Acid Gluconic Acid Saccharic Acid Glucoheptonic Acid Tartaric Acid .alpha.-Hydroxybutyric Acid Tartronic Acid .alpha.-Hydroxyisobutyric Acid Isocitric Acid .alpha.-Hydroxyisocaproic Acid Dihydroxymaleic Acid .alpha.-Hydroxyisovaleric Acid Dihydroxytartaric Acid .beta.-Hydroxybutyric Acid Dihydroxyfumaric Acid [Lactic Acid] .beta.-Phenllactic Acid Atrolactic Acid Mandelic Acid Galactonic Acid Pantoic Acid Glyceric Acid ______________________________________
- or a salt thereof with an organic or inorganic alkali, in a pharmaceutically acceptable vehicle.
A method for alleviating the symptoms of dry skin in humans comprising topically applying an effective amount of at least one member selected from the group consisting of:
- pyruvic acid, benzoylformic acid, .beta.-phenylpyruvic acid, .beta.-hydroxypyruvic acid and .beta.-hydroxypyruvic acid phosphate
- or a salt thereof with an organic or inorganic alkali, in a pharmaceutically acceptable vehicle.
A method for alleviating the symptoms of dry skin in humans comprising an effective amount of at least one member selected from the group consisting of:
- glyceric acid, gluconic acid, glucoheptonic acid, .alpha.-hydroxyisocaproic acid, .alpha.-hydroxyisovaleric acid, atrolactic acid, galatonic acid, isocitric acid, dihydroxymaleic acid, dehydroxytartaric acid, dihydroxyfumaric acid, benzoylformic acid, .beta.-hydroxypyruvic acid, .beta.-hydroxypyruvic acid phosphate, or a salt thereof with an organic or inorganic alkali in a pharmaceutically acceptable vehicle.
Dependencies are inferred from the claim text.