Antibiotic compositions
AssigneeEli Lilly and Company
InventorsRobert N. Hull, Robert S. Gordee
Life of this patent
Estimating the term…
Abstract
Macrolide antibiotics tylosin, spiromycin, cleandomycin, magnamycin, and leucomycin in combination with aminoglycoside antibiotics tobramycin, apramycin, nebramycin 5, gentamicin and neomycin form synergistic compositions which inhibit the growth of mycoplasma in mammalian tissue cultures. Tylosin-apramycin compositions enhance the feed efficiency and weight gain in post weaned pigs and are useful in the control of Pasturella hemolytica an infectious organism in cattle.
Claims3
The synergistic antibiotic composition useful for inhibiting the growth of resistant mycoplasma in mammalian tissue cultures comprising the macrolide antibiotic tylosin or a pharmaceutically acceptable salt thereof and the aminoglycoside antibiotic tobramycin or a pharmaceutically acceptable salt thereof in a weight ratio of tylosin to tobramycin or the pharmaceutically acceptable salts thereof of about 12:1 to about 0.5:12.
Dependencies are inferred from the claim text.