Phenylalanylarginine derivatives, process for producing same and method for measuring activity of enzymes using same
AssigneeTorii & Co., Ltd.
InventorsSetsuro Fujii, Mamoru Sugimito, Takashi Yaegashi
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Abstract
A phenylalanylarginine derivative represented by the formula, ##STR1## wherein R.sub.1 represents hydrogen or an amino-protecting group; R.sub.2 and R.sub.3 represent hydrogen or guanidino-protecting groups; R.sub.4 represents naphthyl. The above compound is useful as an excellent substrate for various enzymes, such as trypsin, plasmin, kallikrein, urokinase, Cl-esterase and the like. Accordingly, the activity of enzymes can be measured by use of said compound as a substrate.
Claims7
A phenylalanylarginine derivative represented by the formula, ##STR18## wherein R.sub.1 represents hydrogen or an amino-protecting group;
- R.sub.2 and R.sub.3 represent hydrogen or guanidino-protecting groups;
- and R.sub.4 represents naphthyl.
L-phenylalanyl-L-arginine 1-naphthyl ester.
Benzoyl-L-phenylalanyl-L-arginine 1-naphthyl ester.
Acetyl-L-phenylalanyl-L-arginine 1-naphthyl ester.
Dependencies are inferred from the claim text.