Vasodilative 4-thia-PGI.sub.1 and 4-sulfinyl-PGI.sub.1 and derivatives thereof

Abstract

A compound having vasodilative, bronchodilative, stomach-mucosa-protective and platelet-aggregation-inhibiting activity has the formula A 4-thia- or 4-sulfinyl-PGI.sub.1 -compound of the formula I ##STR1## wherein Q stands for --S-- or --SO--, A stands for C.sub.1-6 straight or branched chain alkylene, B stands for ethylene, vinylene or ethinylene, R.sup.1 represents hydrogen or C.sub.1-4 alkyl, R.sup.2 represents C.sub.1-8 straight or branched chain alkyl or mono-substituted aryl-oxy-methyl, R.sup.3 stands for hydrogen or acetyl, and Z represents --COOH, --CN, --CH.sub.2 OH or --COOW, wherein W stands for an equivalent of a pharmacologically acceptable cation or C.sub.1-4 alkyl.

Dependencies are inferred from the claim text.