Heterocyclic chemicals, their preparation and use
AssigneeBurroughs Wellcome Co.
InventorsPeter J. Islip, Mirjana V. Bogunovic
Life of this patent
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Abstract
Compounds of formula (III): ##STR1## wherein R.sup.5 is a single substituent in position 2 or 3 of the phenyl ring and when in the 2-position R.sup.5 is a chlorine atom, a methyl group or a nitro group; and R.sup.6 is a hydrogen atom or a CO.CH.sub.3 group may be prepared by methods analogous to those known in the art, for example, by reaction of the corresponding nitrothiazolyl benzamide with the corresponding halo(di)acetamide. The compounds of formula (III) have schistosomicidal activity and may be administered either as the compound alone or as a pharmaceutical formulation.
Claims11
A compound of formula (III) ##STR6## wherein R.sup.5 is a single substituent substituted in a position of the phenyl ring selected from position 2 and position 3 and when in the 2-position R.sup.5 is selected from a chlorine atom, a methyl group and a nitro group and when in the 3-position R.sup.5 is a nitro group;
- and
- R.sup.6 is selected from a hydrogen atom and a CO.CH.sub.3 group.
Dependencies are inferred from the claim text.