Process for preparing oxazolineazetidinone derivatives
AssigneeOtsuka Kagaku Yakuhin Kabushiki Kaisha
InventorsSigeru Torii, Hideo Tanaka, Junzo Nokami, Takashi Shiroi, Norio Saito, Michio Sasaoka
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Abstract
This invention provides a process for preparing an oxazolineazetidinone derivative represented by the formula ##STR1## (wherein R.sup.1 represents hydrogen atom, alkyl group, alkenyl group, substituted or unsubstituted aralkyl group, substituted or unsubstituted aryl group, or substituted or unsubstituted aryloxymethyl group, R.sup.2 represents free or protected carboxyl group and R.sup.3 represents hydrogen atom or methoxy group) from a penicillin derivative represented by the formula ##STR2## wherein R.sup.1, R.sup.2 and R.sub.3 are as defined above.
Claims10
A process for preparing an oxazolineazetidinone derivative represented by the formula (1) ##STR6## wherein R.sup.1 represents hydrogen atom, alkyl group, alkenyl group, substituted or unsubstituted aralkyl group, substituted or unsubstituted aryl group, or substituted or unsubstituted aryloxymethyl group, R.sup.2 represents free or protected carboxyl group and R.sup.3 represents hydrogen atom or methoxy group, the process comprising electrolyzing a penicillin derivative represented by the formula (2) ##STR7## wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above in an alcoholic solvent in the presence of a chloride.
Dependencies are inferred from the claim text.