Tissue culture device for mass cell culture

A multiplate, cell propagation device for use in tissue cultures having a generally elongate enclosed vessel with two end caps and containing a plurality of spaced apart circular discs therein with means for rotating said discs within said vessel, the improvement comprising a cradle-like frame adapted for insertion within said enclosed vessel, said frame having spaced apart end plates secured opposite each other by axially extending rods spaced about the lower and lateral periphery of said end plates, a support shaft on the outer face of one of said end plates for engagement with a shaft bearing recess in the adjacent face of the cap on one end of said vessel and a drive shaft on the outer face of a sealed bearing aperture in the adjacent face of the cap on the other end of said vessel, said axially extending rods between said end plates of said frame being positioned at the lowermost and side portions of the periphery of said end plates to support said plurality of spaced apart discs therein and to permit removal thereof via the uppermost portions thereof.