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US 4,377,576 AGranted
5-(Heterocyclic amino-propionyl)-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-ones
AssigneeKarl Thomae GmbH
InventorsGunther Schmidt, Mario Bergamaschi
Life of this patent
Estimating the term…
Abstract
Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, methyl or ethyl; R.sub.2 is hydrogen or chlorine; R.sub.3 is hydrogen or chlorine; and R.sub.4 is pyrrolidino, piperidino, 2-methyl-piperidino, 2-ethyl-piperidino, 2,6-dimethyl-piperidino or morpholino; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as gastric secretion inhibitors and anti-ulcerogenics.
Claims7
A compound of the formula ##STR7## wherein R.sub.1 is hydrogen, methyl or ethyl;
- R.sub.2 is hydrogen or chlorine;
- R.sub.3 is hydrogen or chlorine;
- and
- R.sub.4 is pyrrolidino, piperidino, 2-methyl-piperidino, 2-ethyl-piperidino, 2,6-dimethyl-piperidino or morpholino;
- or a non-toxic, pharmacologically acceptable acid addition salt thereof.
2 more elements
Dependencies are inferred from the claim text.