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US 4,377,567 AGranted
Lipid membrane drug delivery
AssigneeThe Procter & Gamble Company
InventorWalter B. Geho
Life of this patent
Estimating the term…
Abstract
Lipid Membrane Structures comprising Digalactosyl Diglyceride target the liver of humans and lower animals and are used to carry drugs to that organ, preferentially. Digalactosyl Diglyceride LMS containing insulin provide an effective means for treating diabetes mellitus. Digalactosyl Diglyceride LMS containing interferon are used to treat viral hepatitis.
Claims40
A composition of matter for internal administration in the therapeutic treatment of a human or animal comprising:
- (A) a first component which is a drug or diagnostic agent, said first component being encapsulated in or associated with;
- (B) a second component which comprises lipid membrane structures in the form of vesicles or liposomes, having an average particle diameter of between about 250 Angstroms and about 3000 Angstroms, which comprise a mixture of a major portion of a polar lipid and a minor portion of a digalactosyl derivative having at least one fatty substituent.
Dependencies are inferred from the claim text.