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US 4,377,521 AGranted
Sulfamylbenzoic acids
AssigneePfizer Inc.
InventorGerald F. Holland
Life of this patent
Estimating the term…
Abstract
Certain mono- and disubstituted-5-sulfamylbenzoic acids, many of which are novel, and their use in lowering blood lipid levels in mammals.
Claims10
A compound selected from the group consisting of those of the formula ##STR17## and the amides, lower alkyl esters and salts thereof with pharmacologically acceptable bases, wherein
- U is selected from the group consisting of chloro, fluoro, bromo and di-lower-alkylamino;
- and
- R and R' together with the nitrogen to which they are attached form a heterocyclic ring selected from the group consisting of morpholino, thiomorpholino, piperazinyl, 3-azabicyclo[3,2,2]-nonanyl, tetrahydroisoquinolyl, tetrahydropyridyl and mono- and disubstituted derivatives of said heterocyclic rings;
- said substituents being selected from the group consisting of alkyl, alkyloxy and alkyloxyalkyl of one to four carbon atoms in each alkyl group, hydroxy, chloro, bromo, trifluoromethyl, phenyl, tolyl, benzyl, benzyloxy, chloromethyl and hydroxymethyl.
1 more element
Dependencies are inferred from the claim text.