Process for the production of human erythropoietin
AssigneesKen Hayashibara, Shin Ashida
InventorsKaname Sugimoto, Yasushi Hayashibara
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Abstract
The present invention relates to a process for the production of human erythropoietin. More precisely, the invention relates to a process for the mass production of human erythropoietin, comprising in vivo multiplication of human lymphoblastoid cells capable of producing human erythropoietin, and human erythropoietin production by the multiplied human lymphoblastoid cells. The human erythropoietin production according to the present invention is much higher, in terms of human erythropoietin production per cell, than that attained by conventional processes using in vitro tissue culture; thus, human erythropoietin can be used in a sufficient amount for the prevention and treatment of human diseases.
Claims11
A process for the production of human erythropoietin, comprising
- (1) multiplying human lymphoblastoid cells capable of producing human erythropoietin by transplanting said cells to a non-human warm-blooded animal body, and allowing the multiplied human lymphoblastoid cells to release human erythropoietin, or
- (2) multiplying human lymphoblastoid cells capable of producing human erythropoietin by allowing said cells to multiply with a device by which the nutrient body fluid of a non-human warm-blooded animal is supplied to said cells, and allowing the multiplied human lymphoblastoid cells to release human erythropoietin.
Dependencies are inferred from the claim text.