Basic ethers of 4-hydroxy-benzophenones acting as beta-blocking agents
AssigneeStabilimento Bioterapico Farmacologico La Farmochimica Italiana, S.p.A.
InventorRoberto Montanari
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Abstract
Basic ethers of 4-hydroxy-benzophenones acting as beta-blocking agents, sting from 4-hydroxy-benzophenones and, by reacting them with epichlorohydrin, transforming them into the corresponding 4-O(2', 3'-epoxy-propoxy) derivatives, then reacting with isopropylamine, obtaining the substances according to the invention which can be defined as 4 (gammaisopropylamino-betahydroxypropoxy) benzophenones, wherein the 3 and 4' positions can be represented by: H, Cl and acetyl.
Claims2
A compound of the formula:
- ##STR3## wherein R is hydrogen or chlorine and R.sup.1 is hydrogen or acetyl, and pharmaceutically acceptable salts thereof.
A pharmaceutical beta-blocking composition containing, as an active ingredient thereof, a compound of the formula:
- ##STR4## wherein R is hydrogen or chlorine and R.sup.1 is hydrogen or acetyl, or its pharmaceutically acceptable salts.
Dependencies are inferred from the claim text.