Complexes of square planar platinum II compounds and N-methyl glucamine
AssigneeResearch Corporation
InventorsJohn Turkevich, Joseph H. Burchenal
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Abstract
Complexes or salts of square planar platinum(II) compounds and N-methyl glucamine, prepared by reacting a platinum(II) compound with N-methyl glucamine in an aqueous medium, are effective anti-tumor agents.
Claims21
A cis-complex or -salt prepared by reacting a cis-square planar platinum compound with N-methyl-glucamine wherein two moles of N-methyl-glucamine are reacted with each mole of platinum compound.
A method comprising reacting a cis-square platinum compound, and for each mole thereof two moles of N-methyl-glucamine in an aqueous medium and recovering the cis-complex or -salt of said platinum compound and N-methyl-glucamine formed therein.
Dependencies are inferred from the claim text.