Homocitric acid oligoriboside derivative for prevention of dental caries
AssigneeZaidan Hojin Biseibutsu Kagaku Kenkyu Kai
InventorsYoshiro Okami, Kazuhiko Yamada, Masachika Takashio
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Abstract
Dextransucrase synthesis of dextran from sucrose is inhibited by a novel homocitric acid oligoriboside derivative and its nontoxic salts. The new derivative is obtained by fermentation of certain Streptomyces sp. such as Streptomyces sp. MF 980-CF1 (FERM-P5430; ATCC 31820) and is useful in the prevention of dental caries.
Claims4
The compound ribocitrin having the formula ##STR4## or a nontoxic salt thereof.
An oral composition for caries prophylaxis which comprises a carrier suitable for use in the oral cavity and an effective dextransucrase-inhibiting amount of ribocitrin or a nontoxic salt thereof.
The method of inhibiting dextransucrase synthesis of dextran from sucrose which comprises introducing into the oral cavity an effective dextransucrase-inhibiting amount of ribocitrin or a nontoxic salt thereof.
Dependencies are inferred from the claim text.