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US 4,376,071 AGranted
Mitogenic spinal cord growth factor
AssigneeResearch Corporation
InventorsThomas J. Jennings, Allan Lipton
Life of this patent
Estimating the term…
Abstract
A proteinaceous factor substantially purified from mammalian spinal cord which has mitogenic activity, a molecular weight of about 11,000, a pI of 9.6 and which is heat and acid labile, is useful for the promotion of growth of cells.
Claims13
A substantially purified proteinaceous factor obtained from spinal cord which has mitogenic activity, a molecular weight of about 11,000, a pI of 9.6 and which is heat and acid labile.
A process of purifying a mitogenic factor from mammalian spinal cord which comprises:
- homogenizing mammalian spinal cord;
- separating said homogenate into a solids fraction and a liquid fraction;
- fractionating from said liquid fraction molecules which lie in the range of molecular weights 10,000-15,000.
Dependencies are inferred from the claim text.