Dioxalane containing imidazole compounds, compositions and use

A composition useful for inhibiting the growth of fungi, bacteria or protozoa which comprises an effective amount of a compound of the formula ##STR18## in admixture with a suitable carrier;

• wherein:
• Z is oxygen or sulfur;
• R.sup.1 is phenyl optionally substituted with one or more substituents selected from the group consisting of halo, lower alkyl, lower alkoxy and trifluoromethyl;
• R.sup.2 is phenyl or benzyl wherein the phenyl ring of R.sup.2 is optionally substituted by one or more substituents selected from the group consisting of halo, lower alkyl, lower alkoxy and trifluoromethyl;
• or a phenyl optionally substituted by halo, lower alkyl, lower alkoxy and trifluoromethyl;
• or an antimicrobial acid addition salt thereof.

A method of inhibiting the growth of fungi, bacteria or protozoa which comprises applying to a host object containing, or subject to attack by, fungi, bacteria or protozoa an effective amount of a compound of the formula ##STR19## wherein:

• Z is oxygen or sulfur;
• R.sup.1 is phenyl optionally substituted with one or more substituents selected from the group consisting of halo, lower alkyl, lower alkoxy and trifluoromethyl;
• R.sup.2 is phenyl or benzyl wherein the phenyl ring of R.sup.2 is optionally substituted by one or more substituents selected from the group consisting of halo, lower alkyl, lower alkoxy and trifluoromethyl;
• or a phenyl optionally substituted by halo, lower alkyl, lower alkoxy or trifluoromethyl;
• or a composition containing same as an active ingredient.