Constant order release aspirin composition and method of treating arthritis
AssigneeVerex Laboratories, Inc.
InventorJames M. Dunn
Life of this patent
Estimating the term…
Abstract
A constant order release aspirin tablet comprising aspirin, from 0.5 to 10 weight percent of a hydrogenated vegetable oil and from 0.5 to 7 weight percent of a saccharide selected from the group consisting of lactose, sucrose, dextrose fructose and maltose. The aspirin tablet is administered once or twice a day for the chronic treatment of arthritis, and has substantially lessened gastrointestinal side effects.
Claims13
A constant order release aspirin tablet comprising aspirin, from 0.5 to 10 weight percent of a hydrogenated vegetable oil, from 0.5 to 7.0 weight percent of a saccharide selected from the group consisting of lactose, sucrose, dextrose, fructose and maltose, and a lubricant.
A constant order release aspirin tablet comprising aspirin, from 0.5 to 10 weight percent of hydrogenated cottonseed oil, from 0.5 to 7.0 weight percent of lactose and a lubricant.
A constant order release aspirin tablet comprising aspirin, from 0.5 to 10 weight percent of hydrogenated cottonseed oil, from 0.5 to 7.0 weight percent of lactose, from 0.15 to 1.5 weight percent of a cellulose ether, cellulose ester or a combination thereof, and a lubricant.
A method of producing a control release aspirin tablet comprising the steps of dissolving from 0.5 to 10 weight percent of a hydrogenated vegetable oil in a suitable solvent, admixing said solution with a dry-blended mixture of from 85 to 98 weight percent of aspirin and from 0.5 to 7.0 weight percent of a saccharide selected from the group consisting of lactose, sucrose, dextrose, fructose and maltose to form a wet granulation, drying said wet granulation, sizing said granules, blending said sized granules with a lubricant and thereafter compressing said dried, sized granules into tablets.
Dependencies are inferred from the claim text.