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US 4,374,981 AGranted
Ultrafiltration of fermentation broth containing nucleosides to separate inosine and guanosine from the broth
AssigneeTakeda Chemical Industries, Ltd.
InventorsMasahiko Tsuda, Kazuhiko Ohta, Kiyoshi Nara
Life of this patent
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Abstract
Inosine and/or guanosine can be separated from fermentation broth containing microbial cells and high-molecular-weight substances by heat-treating said broth at 90.degree. to 110.degree. C., followed by subjecting to ultrafiltration. The present process is advantageously carried out in the industrial use of ultrafiltration.
Claims2
A process for separating inosine, guanosine or their mixture from a fermentation broth, which comprises heat-treating said fermentation broth at 90.degree. to 110.degree. C., followed by subjecting thus-heated fermentation broth to ultrafiltration.
Dependencies are inferred from the claim text.