5-ASA Drug delivery system
AssigneeG. D. Searle & Co.
InventorsBarnett S. Pitzele, Peter H. Jones
Life of this patent
Estimating the term…
Abstract
The present invention relates to novel compounds for the prophylaxis and treatment of Inflammatory Bowel disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage of a polymeric agent for releasing 5,5'-azobis-salicylic acid which comprises a non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis-salicylic acid. The 5,5'-azobis-salicylic acid undergoes bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid.
Claims2
A polymeric anionic exchange complex comprising a pharmacologically acceptable, non-absorbable, non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis salicylic acid.
Dependencies are inferred from the claim text.