US 4,374,844 A · Stable derivatives of (5R,6S,8R)-6-hydroxyethyl-2-ethylthiopenem-3-carboxylic acids

Abstract

Sodium and Potassium (5R,6S,8R)-6-(1-hydroxyethyl)-2-ethylthiopenem-3-carboxylic acid exhibit potent, broad-spectrum antibacterial activity, are orally effective and chemically stable.

Claims10

Dependent claims

Sodium (5R,6S,8R)-6-(1-hydroxyethyl)-2-ethylthiopenem-3-carboxylate substantially free from its enantiomer.

Dependencies are inferred from the claim text.

Facts

Application

06/316,627Filed 30 Oct 1981 · continuation in part

Priority

EP 80810004.47 Jan 1980

Granted

22 Feb 1983

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C07F 7/10
Compounds having one or more C—Si linkages: containing nitrogen having a Si-N linkage
C07D 205/08
Having one double bond between ring members or between a ring member and a non-ring member: with one oxygen atom directly attached in position 2,…
C07D 205/09
With one oxygen atom directly attached in position 2, e.g. beta-lactams: with a sulfur atom directly attached in position 4
C07D 499/88
Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:…

Family

Serial2,471Parent of this continuation-in-part · filed 10 Jan 1979

Serial62,875Parent of this continuation-in-part · filed 1 Aug 1979

Serial91,610Parent of this continuation-in-part · filed 5 Nov 1979

Serial219,410Parent of this continuation-in-part · filed 22 Dec 1980

US 4,374,844 AThis patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Sodium and Potassium (5R,6S,8R)-6-(1-hydroxyethyl)-2-ethylthiopenem-3-carboxylic acid exhibit potent, broad-spectrum antibacterial activity, are orally effective and chemically stable.

Facts

Application

06/316,627Filed 30 Oct 1981 · continuation in part

Priority

EP 80810004.47 Jan 1980

Granted

22 Feb 1983

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C07F 7/10
Compounds having one or more C—Si linkages: containing nitrogen having a Si-N linkage
C07D 205/08
Having one double bond between ring members or between a ring member and a non-ring member: with one oxygen atom directly attached in position 2,…
C07D 205/09
With one oxygen atom directly attached in position 2, e.g. beta-lactams: with a sulfur atom directly attached in position 4
C07D 499/88
Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:…

Family

Serial2,471Parent of this continuation-in-part · filed 10 Jan 1979

Serial62,875Parent of this continuation-in-part · filed 1 Aug 1979

Serial91,610Parent of this continuation-in-part · filed 5 Nov 1979

Serial219,410Parent of this continuation-in-part · filed 22 Dec 1980

US 4,374,844 AThis patent

From the US filing history. Foreign family members aren’t listed.

Stable derivatives of (5R,6S,8R)-6-hydroxyethyl-2-ethylthiopenem-3-carboxylic acids

Life of this patent

Abstract

Claims10

Stable derivatives of (5R,6S,8R)-6-hydroxyethyl-2-ethylthiopenem-3-carboxylic acids

Life of this patent

Abstract

Claims10