Process for enzymatically producing L-carnitine
AssigneeSigma-Tau Industrie Farmaceutiche Riunite S.p.A.
InventorClaudio Cavazza
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Abstract
An enzymatic process for producing L-carnitine is disclosed which comprises contacting a solution in a hydroxyl group donor solvent of .gamma.-butyrobetaine, sodium-2-oxoglutarate, a reducing agent and a ferrous salt as a hydroxylation catalyst with a phase comprising a spore preparation of the mold Neurospora crassa.
Claims9
A process for the preparation of L-carnitine which comprises contacting .gamma.-butyrobetaine in the presence of sodium 2-oxoglutarate, a reducing agent, a source of ferrous ions and a hydroxyl group donor solvent, with a source of the hydroxylase enzyme released from the spores of Neurospora crassa.
Dependencies are inferred from the claim text.