1,3-Diaryl-2-imino-imidazolidines and compounds
AssigneeEgyt Gyogyszervegyeszeti Gyar
InventorsLajos Toldy, Zoltan Zubovics, Mariann Kurti, Inge Schafer
Life of this patent
Estimating the term…
Loading patent…
AssigneeEgyt Gyogyszervegyeszeti Gyar
InventorsLajos Toldy, Zoltan Zubovics, Mariann Kurti, Inge Schafer
Estimating the term…
A compound of the general formula (I), ##STR1## is described wherein R.sup.1 and R.sup.5 each represent a phenyl group optionally substituted with 1 to 3 lower alkoxy, halo, lower alkyl, monohalo-(lower)-alkyl, dihalo-(lower)-alkyl and/or trihalo-(lower)-alkyl groups, R.sup.2 stands for hydrogen or a lower alkyl group optionally substituted with a hydroxy group or 1 to 3 halogen atoms, R.sup.3 and R.sup.4 each represent a hydrogen atom or a lower alkyl group, and R.sup.6 stands for a carbamoyl, thiocarbamoyl or amidino group having optionally one or two lower alkyl and/or lower alkoxycarbonyl substitutes, or a group of the general formula R.sup.7 -CO-wherein R.sup.7 stands for a lower analkoxy group, an aryloxy group, or an aralkoxy group, and n is equal to 0, provided that when R.sup.1 and R.sup.5 each represent a phenyl group, R.sup.2 and R.sup.3 may not stand for hydrogen or a pharmaceutically acceptable acid addition salt, a pure isomer or an isomeric mixture thereof. The compounds posses antiphlogistic and diuretic activity.
A compound of the general formula (I), ##STR7## wherein R.sup.1 and R.sup.5 each represent a phenyl group optionally substituted with 1 to 3 lower alkoxy, halo, lower alkyl, monohalo-(lower)-alkyl, dihalo-(lower)-alkyl and/or trihalo-(lower) alkyl groups,
1,3-Bis(2',6'-dimethylphenyl)-2-carbethoxy-imino-4 methyl-imidazolidine.
1,3-Bis(2',6'-dimethylphenyl)-2-(p-methoxy-benzyloxy-carbonyl)-imino-4-m ethyl-imidazolidine.
1-[1',3'-Bis(2",6 "-dimethylphenyl)-4'-methyl-imidazolidin-2'-ylidene]-3-carbethoxy-thiourea.
Dependencies are inferred from the claim text.