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US 4,364,943 AGranted
Syn-isomer of 7-[2-alkoxyimino-2-(2-amino-alkanoylamino-or haloalkanoylamino-thiazol-4-yl) acetamids]-3-[hexanoyl-, or phenylalkanoyl-oxymethyl or benzothiazolylthiomethyl]-3-cephem-4-carboxylic acid
AssigneeFujisawa Pharmaceutical Co., Ltd.
InventorsTakao Takaya, Takashi Masugi, Hisashi Takasugi, Hiromu Kochi
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Abstract
Syn-isomers of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and pharmaceutically acceptable salts thereof which have anti-bacterial activities and the processes for the preparation thereof, to pharmaceutically composition comprising the same, and to a method of using the same therapeutically and the treatment of infectious diseases in animals and human beings.
Claims8
Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds of the formula:
- ##STR24## in which ##STR25## wherein R.sup.7 is amino, lower alkanoylamino or halo(lower)alkanoylamino;
- R.sup.2 is lower alkyl;
- R.sup.3 is carboxy;
- and
- R.sup.4 is hexanoyloxymethyl, phenyl(lower)alkanoyloxymethyl, or benzothiazolylthiomethyl;
- and
- pharmaceutically acceptable salts thereof.
4 more elements
The compound of claim 7, wherein
- R.sup.7 is lower alkanoylamino and
- R.sup.4 is benzothiazolylthiomethyl.
Dependencies are inferred from the claim text.