Extraction of interferon from bacteria
AssigneeSchering Corporation
InventorsPaul Leibowitz, Marvin J. Weinstein
Life of this patent
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Abstract
A method of extracting leucocyte interferon from interferon-expressing bacterial cells comprising acidifying a suspension of interferon-containing bacterial cells, removing substantially all of the suspension liquid from the cells, preparing a second suspension of the acidified cells, neutralizing said second suspension, separating the interferon containing liquid from the suspended cells, and extracting the interferon from said liquid.
Claims8
A method of extracting fibroblast interferon from interferon-expressing bacterial cells comprising acidifying a suspension of interferon-containing bacterial cells, removing substantially all of the suspension liquid from the cells, preparing a second suspension of the acidified cells, neutralizing said second suspension, separating the interferon containing liquid from the suspended cells, and extracting the interferon from said liquid.
Dependencies are inferred from the claim text.