Process for producing L-tryptophan, and a pure culture of a microorganism strain used in said process
AssigneeShowa Denko K.K.
InventorsTakeo Akashiba, Akira Nakayama, Atsuhiko Murata
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Abstract
In a process for producing L-tryptophan which comprises cultivating an L-tryptophan-producing mutant of Bacillus subtilis under aerobic conditions in a nutrient culture medium containing anthranilic acid, a carbon source, a nitrogen source and a mineral source, and recovering the resultant L-tryptophan from the culture broth, the improvement wherein the mutant is a strain resistant to 5-fluorotryptophan and 8-azaguanine; and a pure culture of a microorganism strain used in said process.
Claims6
In a process for producing L-tryptophan which comprises cultivating an L-tryptophan-producing mutant of Bacillus subtilis under aerobic conditions in a nutrient culture medium containing anthranilic acid, a carbon source, a nitrogen source and a mineral source, and recovering the resultant L-tryptophan from the culture broth, the improvement wherein the mutant is a strain resistant to 5-fluorotryptophan and 8-azaguanine.
A biologically pure culture of Bacillus subtilis SD-10 strain which has the characteristics identified as FERM BP-4 deposited under the Budapest Treaty and has the ability to produce L-tryptophan by fermentation in a nutrient culture medium containing anthranilic acid, a carbon source, a nitrogen source and a mineral source under aerobic conditions.
Dependencies are inferred from the claim text.