Oral composition for caries prophylaxis
AssigneeLion Corporation
InventorsYoshihito Ochiai, Syozi Nakashima, Midori Hayashi
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Abstract
An oral composition is disclosed which comprises a stannous salt such as stannous fluoride, a water-soluble fluoride salt such as sodium fluoride and an orally acceptable acid such as L-ascorbic acid, lactic acid, malonic acid, tartaric acid, citric acid, hydrochloric acid and pyrophosphoric acid, the molar ratio of fluoride ion to stannous ion being in the range of 3.2 to 7:1, preferably 3.5-6:1, in an aqueous condition and the pH of the composition being in the range of from 2 to 4. The composition exhibits excellent effects on the inhibition of dental caries.
Claims8
An oral composition for caries prophylaxis comprising a stannous salt, a water-soluble fluoride salt selected from the group consisting of sodium fluoride, potassium fluoride and mixtures thereof, and an orally acceptable acid selected from the group consisting of a monocarboxylic acid, a dicarboxylic acid, a tricarboxylic acid, a mineral acid and mixtures thereof, said stannous salt being present in the range of from 0.07% by weight of the total amount of the composition as stannous ion to the saturated state in water, the molar ratio of fluoride ion to stannous ion being in the range of from 3.5:1 to 5.7:1 in the aqueous condition, the molar ratio of said monocarboxylic acid to stannous ion being in the range of from 0.8.times.0.5.sup.n :1 to 30.times.0.6.sup.n :1, the exponent "n" being the weight percent content of the stannous ion in the composition, and said orally acceptable acid being present in the composition in such an amount that the pH of the composition is in the range of from 2 to 4.
An oral composition for caries prophylaxis comprising a stannous salt, a water-soluble fluoride salt selected from the group consisting of sodium fluoride, potassium fluoride and mixtures thereof, and an orally acceptable acid selected from the group consisting of a monocarboxylic acid, a dicarboxylic acid, a tricarboxylic acid, a mineral acid and mixtures thereof, said stannous salt being present in the range of from 0.07% by weight of the total amount of the composition as stannous ion to the saturated state in water, the molar ratio of fluoride ion to stannous ion being in the range of from 3.5:1 to 5.7:1 in the aqueous condition, the molar ratio of the acid selected from the group consisting of a dicarboxylic acid, a tricarboxylic acid and a mineral acid to stannous ion being in the range of from 0.2.times.0.6.sup.n :1 to 5.times.0.6.sup.n :1, the exponent "n" being the weight percent content of the stannous ion in the composition, and said orally acceptable acid being present in the composition in such an amount that the pH of the composition is in the range of from 2 to 4.
Dependencies are inferred from the claim text.