US 4,362,866 A · Aprosamine derivatives

Abstract

New aprosamine derivatives having the reinforced antimicrobial activity against gram-positive and negative bacteria with less side effects than apramycin, and produced by chemical modification of 8'-hydroxy group of aprosamine obtained by means of hydrolysis of apramycin.

Claims2

Dependent claims

An aprosamine derivative having the following general formula and its pharmaceutically acceptable acid addition salts:

##STR6## (wherein n is 0 or 1;
the wave line indicates axial or equatorial configuration).

Dependencies are inferred from the claim text.

Facts

Application

06/313,971Filed 22 Oct 1981

Priority

JP 55-15092627 Oct 1980

Granted

7 Dec 1982

Term ends

Not estimatedThe source records don’t support an estimate.

Classification6 codes

C07H 15/224
Cyclohexane rings substituted by at least two nitrogen atoms: with only one saccharide radical directly attached to the cyclohexyl radical, e.g.…
A61P 31/04
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antibacterial agents
Y02P 20/55
Improvements relating to the production of bulk chemicals: design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
C07H
Sugars

Aprosamine derivatives

Life of this patent

Abstract

Claims2

Aprosamine derivatives

Life of this patent

Abstract

Claims2