Antiviral 1,2,3,4-tetrahydro-1,4-methanonaphthalene derivatives
AssigneesCanada Packers Limited, The Institute of Microbiology and Hygiene of the University of Montreal
InventorsKekhusroo R. Bharucha, Kam C. Tin, Iva Ajdukovic, Djordje Ajdukovic
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Abstract
Derivatives of 1,2,3,4-tetrahydro-1,4-methanonaphthalene, and the use of h compounds to control viral infections, particularly influenza virus, in warm-blooded animals are disclosed. Pharmaceutical compositions containing an antiviral effective amount of the novel compounds and a pharmaceutically acceptable carrier are also disclosed.
Claims8
Endo-3-dimethyla minomethyl-endo-2-amino-1,2,3,4-tetrahydro-1,4-methanonaphthalene and its pharmaceutically acceptable acid addition salts.
Endo-2-dimethylaminomethyl-1,2,3,4-tetrahydro-1,4-methanonaphthalene and its pharmaceutically acceptable acid addition salts.
A composition of matter comprising an anti-viral effective amount of a compound selected from the group consisting of endo-3-dimethylaminomethyl-endo-2-amino-1,2,3,4-tetrahydro-1,4-methanonaph thalene, endo-2-dimethylaminomethyl-1,2,3,4-tetrahydro-1,4-methanonaphthalene and their pharmaceutically acceptable acid addition and a pharmaceutically acceptable carrier.
A method for treating viral infections in a patient comprising administering to the patient an effective daily dose of a compound selected from the group consisting of endo-3-dimethylaminomethyl-endo-2-amino-1,2,3,4-methanonaphthalene, endo-2-dimethylaminomethyl-1,2,3,4-tetrahydro-1,4-methanonaphthalene and their pharmaceutically effective acid addition salts.
Dependencies are inferred from the claim text.