N-Cyclopropylmethyl-14-ethoxymorphinan-6-one compounds exhibiting mixed analgesic/narcotic antagonist activity and precursors therefore
AssigneeMiles Laboratories, Inc.
InventorsAnil C. Ghosh, Raj K. Razdan
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Abstract
Disclosed are certain 14-ethoxymorphinan-6-one compounds exhibiting analgesic and, in some cases, mixed analgesic/narcotic antagonist activity.
Claims10
14-ethoxy substituted-3-hydroxy or 3-methoxy-6-one morphinans characterized by the formula:
- ##STR8## wherein R is H or methyl and R.sub.1 is methyl or cyclopropylmethyl.
A therapeutic method for treating pain in an individual for whom such therapy is indicated, which method comprises administering to the individual an effective analgesic amount of a compound characterized by the formula:
- ##STR9## where R is H or methyl.
A therapeutic method for treating pain without liability of drug dependence in an individual for whom such therapy is indicated which method comprises administering to the individual an effective analgesic amount of a compound characterized by the formula:
- ##STR10## where R is H or methyl.
Dependencies are inferred from the claim text.