Myotonolytic use of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridin-3-ol and derivatives thereof
AssigneeSandoz Ltd.
InventorRonald C. Hill
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Abstract
The myotonolytic use of compounds of formula I ##STR1## wherein R is hydrogen, acetyl or a group of formula II R'--O--CO-- II wherein R' is alkyl(C.sub.1-8); phenyl; phenyl substituted in the 4-position with halogen, alkoxy(C.sub.1-4) or alkyl(C.sub.1-4); phenylalkyl; or phenylalkyl in which the phenyl group is substituted in the 4-position with halogen, alkoxy(C.sub.1-4) or alkyl(C.sub.1-4).
Claims8
A method of treating myotonic conditions in a subject in need of such treatment, which method comprises administering to said subject a myotonolytically effective amount of a compound of formula I ##STR4## wherein R is hydrogen, acetyl or a group of formula II
- R'--O--CO-- II
- wherein R' is alkyl(C.sub.1-8);
- phenyl;
- phenyl substituted in the 4-position with halogen, alkoxy (C.sub.1-4 ) or alkyl(C.sub.1-4);
- phenyalkyl;
- or phenylalkyl in which the phenyl group is substituted in the 4-position with halogen, alkoxy(C.sub.1-4) or alkyl(C.sub.1-4).
Dependencies are inferred from the claim text.