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US 4,362,697 AGranted
Homogeneous specific binding assay test device having copolymer enhancing substance
AssigneeMiles Laboratories, Inc.
InventorsDavid L. Tabb, Richard J. Tyhach
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Abstract
A test device for performing homogeneous specific binding assays is composed of a carrier matrix having incorporated therein reagents and an enhancer substance. The enhancer substance is a copolymer of vinyl pyrrolidone and a type of acrylic comonomer.
Claims5
A test device for determining the presence of a ligand in, or the ligand binding capacity of a liquid sample, comprising
- (a) reagents for a homogeneous specific binding assay system capable of producing a detectable response which is a function of the presence of the ligand in or the ligand binding capacity of the sample;
- (b) an enhancer substance comprising a quaternized copolymer of vinylpyrrolidone and a comonomer having the structure ##STR3## in which R, same or different, is lower alkyl, R' is H or lower alkyl and R" is lower alkylene;
- and
- (c) a carrier matrix incorporated with said reagents and enhancer substance.
1 more element
Dependencies are inferred from the claim text.