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US 4,362,663 AGranted
Maytansinoid compound
AssigneeTakeda Chemical Industries, Ltd.
InventorsMakoto Kida, Motowo Izawa, Kazuo Nakahama
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Abstract
Antibiotic C-15003 PND of the formula: ##STR1## wherein R is H or alkanoyl containing not more than 5 carbon atoms is produced by contacting a maytansinoid compound with a culture broth, inclusive of a processed matter derived therefrom, of a microorganism belonging to one of the genera Streptomyces and Chainia which is able to transform said maytansinoid compound into Antibiotic C-15003 PND. Antibiotic C-15003 PND is useful as antitumor, antifungal or antiprotozoal agent.
Claims1
A compound of the formula:
- ##STR14##
Dependencies are inferred from the claim text.