Method for stabilizing plasminogen
AssigneeThe Green Cross Corporation
InventorsYahiro Uemura, Katuhiro Uriyu, Satoshi Funakoshi
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Abstract
A method for stabilizing plasminogen which comprises adding a physiologically acceptable inorganic salt to a plaminogen-containing aqueous solution to give a final concentration of the salt of 0.002 to 0.4 M.
Claims3
In a method for producing a plasminogen preparation comprising adding a physiologically acceptable inorganic salt to a plasminogen-containing aqueous solution to give a final concentration of the salt of 0.002 to 0.4 M and heat-treating the aqueous solution at 60.degree. C. for 10 hours, the improvement which comprises subjecting the aqueous solution to digestion at 4.degree. to 37.degree. C. at pH 2 to 4 for 2 to 60 minutes before the heat-treatment.
Dependencies are inferred from the claim text.