Polycyclic ether antibiotic
AssigneePfizer Inc.
InventorsWalter D. Celmer, Walter P. Cullen, Riichiro Shibakawa, Junsuke Tone
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Abstract
A new acidic polycyclic ether antibiotic has the formula: ##STR1## and can be prepared by the submerged aerobic propagation in aqueous nutrient media of Streptomyces halstedii ATCC 31812. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth in poultry and ruminants.
Claims3
A process for producing the antibiotic of the formula ##STR3## or the pharmaceutically acceptable salts thereof which comprises cultivating the microorganism Streptomyces halstedii ATCC 31812 in aqueous culture media containing an assimilable source of carbon, nitrogen and inorganic salts under submerged aerobic fermentation conditions until a substantial amount of said antibiotic is obtained.
Dependencies are inferred from the claim text.