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AssigneeChugai Seiyaku Kabushiki Kaisha
InventorsSakae Takaku, Fumiaki Matsuura, Takashi Mori, Yasushi Murakami, Shigeyuki Kataoka, Yasuhisa Takeda, Yasuhiro Yamashita, Yumiko Takeda, Takashi Matsuno, Koji Mizuno, Shinichi Kaiho, Tamotsu Yamazaki, Shun-ichi Hata, Shigeru Takanashi
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1,4,5,6-Tetrahydronicotinamide derivative represented by the formula: ##STR1## (wherein R is defined in the specification), a process of preparing the same and pharmaceutical composition containing the same are disclosed. The compound has action for suppressing aggregation of platelets, and antiinflammatory, antipyretic and analgesic actions.
A 1,4,5,6-tetrahydronicotinamide derivative of the formula:
N-(1,4,5,6-Tetrahydronicotinoyl)-2-methoxyaniline.
N-(1,4,5,6-Tetrahydronicotinoyl)-3-methoxyaniline.
N-(1,4,5,6-Tetrahydronicotinoyl)-4-methoxyaniline.
N-(1,4,5,6-Tetrahydronicotinoyl)-2,5-dimethoxyaniline.
N-(1,4,5,6-Tetrahydronicotinoyl)-2-ethoxyaniline.
N-(1,4,5,6-Tetrahydronicotinoyl)-2-methylaniline.
N-(1,4,5,6-tetrahydronicotinoyl)-2,6-dimethylaniline.
N-(1,4,5,6-Tetrahydronicotinoyl)-2-fluoroaniline.
N-(1,4,5,6-Tetrahydronicotinoyl)aniline.
2-(1,4,5,6-Tetrahydronicotinamido)pyridine.
Dependencies are inferred from the claim text.