Pyridazinone-substituted benzimidazoles and salts
AssigneeDr. Karl Thomae GmbH
InventorsVolkhard Austel, Joachim Heider, Wolfgang Eberlein, Willi Diederen, Walter Haarmann
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AssigneeDr. Karl Thomae GmbH
InventorsVolkhard Austel, Joachim Heider, Wolfgang Eberlein, Willi Diederen, Walter Haarmann
Estimating the term…
Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen; trifluoromethyl; alkyl of 1 to 11 carbon atoms; cycloalkyl of 3 to 7 carbon atoms; hydroxyl; alkoxy of 1 to 6 carbon atoms; mercapto; (alkyl of 1 to 6 carbon atoms)-mercapto; phenyl-(alkyl of 1 to 3 carbon atoms); phenyl; or mono-, di- or tri-substituted phenyl, where the substituents, which may be identical to or different from each other, are each halogen, alkyl of 1 to 4 carbon atoms, (alkyl of 1 to 6 carbon atoms)-sulfinyl, hydroxyl, alkoxy of 1 to 6 carbon atoms, mercapto or (alkyl of 1 to 6 carbon atoms)-mercapto; R.sub.2 is hydrogen, alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 6 carbon atoms or phenyl-(alkyl of 1 to 3 carbon atoms); and R.sub.3 is alkyl of 1 to 6 carbon atoms; optically active antipodes thereof; and non-toxic, pharmaceutically acceptable acid addition salts of said compounds or of said optically active antiposed. The compounds are useful as cardiotonics and antithrombotics.
A compound of the formula ##STR7## wherein R.sub.1 is hydrogen;
Dependencies are inferred from the claim text.