Sulfonated alkoxynaphthalenes as dental plaque barriers
AssigneeJohnson & Johnson Products, Inc.
InventorCarl J. Buck
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Abstract
Compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated alkoxynaphthalenes and the pharmaceutically acceptable salts thereof. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.
Claims6
An alkoxynaphthalene sulfonic acid compound having a structure selected from the group consisting of structure (A), ##STR6## structure (B), ##STR7## and structure (C), ##STR8## wherein R.sub.1 is a linear or branched alkyl having 6 to 20 carbon atoms, R.sub.2 is a linear or branched alkyl having 8 to 20 carbon atoms, and M is selected from the group consisting of hydrogen, lithium, sodium, potassium, calcium, magnesium, zinc, aluminum, ammonium and the substituted ammonium ions derived from pharmaceutically acceptable organic amines.
An oral hygiene composition comprising a therapeutically effective amount for preventing deposition of dental plaque on teeth of an alkoxynaphthalene sulfonic acid compound having a structure selected from the group consisting of structure (A), ##STR9## and structure (B), ##STR10## and structure (C), ##STR11## wherein R.sub.1 is a linear or branched alkyl having 6 to 20 carbon atoms, R.sub.2 is a linear or branched alkyl having 8 to 20 carbon atoms, and M is selected from the group consisting of lithium, sodium, potassium, calcium, magnesium, zinc, aluminum, hydrogen, ammonium, and substituted ammonium ions derived from pharmaceutically acceptable organic amines, in a pharmaceutically acceptable oral hygiene vehicle compatible with said polymer.
Dependencies are inferred from the claim text.