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US 4,360,472 AGranted
Trihydroxyvitamin D.sub.3 compounds
AssigneeWisconsin Alumni Research Foundation
InventorsHector F. DeLuca, Heinrich K. Schnoes, Joseph K. Wichmann
Life of this patent
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Abstract
A novel side chain trihydroxylated vitamin D.sub.3 compound, namely 23,24,25-trihydroxyvitamin D.sub.3 and its acylated and alkylsilyated derivatives are provided. The new compounds are hydroxy analogs of the biologically-active 25-hydroxyvitamin D.sub.3 and would find application as substitutes for such compound or for vitamin D.sub.3.
Claims4
A compound having the formula:
- ##STR2## wherein each of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is selected from the group consisting of hydrogen, acyl and alkylsilyl.
23,24,25-trihydroxyvitamin D.sub.3.
Dependencies are inferred from the claim text.