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US 4,359,529 AGranted
Microbial process for producing cholanic acid derivatives
AssigneeKuraray Co., Ltd.
InventorsMasao Tsuji, Yoshihiro Ichihara
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Abstract
A microbial process for producing a cholanic acid derivative of the formula: ##STR1## wherein X is ##STR2## or .dbd.O; and R is hydrogen, an alkali metal or an alkaline earth metal, which comprises cultivating a microbe which is capable of growing in a medium containing cholic acid or a salt thereof as a substrate to produce the cholanic acid derivative, selected from the genera Arthrobacter, Brevibacterium and Corynebacterium, in a culture medium containing the substrate and collecting the resulting derivative.
Claims10
A microbial process for producing a cholanic acid derivative of the formula:
- ##STR7## wherein X is ##STR8## or .dbd.O;
- and R is hydrogen, an alkali metal or an alkaline earth metal, which comprises cultivating a microbe which is capable of growing in a medium containing cholic acid or salt thereof as a substrate to produce the cholanic acid derivatice and is selected from the group consisting of Arthrobacter sp., Brevibacterium sp. and Corynebacterium sp., in a culture medium containing the substrate and collecting the resulting derivative.
Dependencies are inferred from the claim text.