Preparation of fluorinated anthranilic acid and anthranilonitrile
AssigneeBASF SE
InventorsPeter Jacobs, Heinz-Guenter Oeser
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Abstract
Fluorinated anthranilic acid and anthranilonitrile, and a novel process for their preparation by reacting 2,6-difluorobenzonitrile with ammonia and, if the acid is required, hydrolyzing the resulting 6-fluoroanthranilonitrile with a basic compound. The two novel end products are valuable intermediates for the preparation of compounds which are useful for controlling various animal pests and plant pests.
Claims14
A process for the preparation of 6-fluoroanthranilic acid or its nitrile, of the formula ##STR7## where R is --COOH or --CN respectively, wherein (a) 2,6-difluorobenzonitrile of the formula ##STR8## is reacted with ammonia and thereafter, if the acid is desired, (b) the resulting 6-fluoroanthranilonitrile of the formula ##STR9## is reacted with a basic compound.
A process for the preparation of the 6-fluoroanthranilonitrile of the formula ##STR10## which comprises:
- reacting 2,6-difluorobenzonitrile with ammonia at a temperature of from 0.degree. to 200.degree. C.
A process for the preparation of 6-fluoroanthranilic acid of the formula ##STR11## which comprises:
- reacting the 6-fluoroanthranilonitrile of the formula ##STR12## with a basic compound at a pH of from 7 to 14 and at a temperature of from 0.degree. to 150.degree. C.
Dependencies are inferred from the claim text.