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US 4,358,585 AGranted
5-Deoxyapramycin
AssigneeShionogi & Co., Ltd.
InventorsKikuo Igarashi, Tsunetoshi Honma, Tamio Sugawara
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Abstract
Novel 5-deoxyapramycin having the reinforced antimicrobial activity against gram-positive and negative bacteria with less side effects, resulted from reductive removal of 5-hydroxy group of apramycin through halogenation.
Claims1
5-Deoxyapramycin represented by the following formula and the pharmaceutically acceptable acid addition salts thereof ##STR5## .
Dependencies are inferred from the claim text.