Substituted 3-aryl-2-cycloalken-1-one and method of preparation thereof

Abstract

There is disclosed substituted alkenones of Formula I ##STR1## wherein R.sup.1 is alkyl or acylamino each having 1 to 4 carbon atoms, hydrogen, or halogen, R.sup.2 and R.sup.3 individually are hydrogen, methyl or ethyl, R.sup.4 is hydrogen or dimethoxyphenyl, and n is 1 or 2, or physiologically acceptable acid addition salts thereof. Intermediates are also disclosed, along with methods of preparation of both the intermediates and the end products. The end products are useful as .beta. adrenolytic and anti-hypertensive agents. They are useful in the treatment of angina pectoris, hypertension, and arrhythmia.

Dependencies are inferred from the claim text.