1,3,4-Triazolo[1,5-a]pyridines

A compound represented by the formula:

• ##STR13## and the pharmaceutically acceptable salts thereof, wherein R represents hydrogen, lower alkyl of 1-3 carbons, arylalkyl, --CH.sub.2 OH, --CH.sub.2 CN, ##STR14## --NO.sub.2, --NO, --CH.sub.2 --O--CO--R.sub.1, (wherein R.sub.1 is lower alkyl or dimethylaminomethyl), --N(R.sub.3).sub.2 (wherein each R.sub.3 independently is hydrogen, lower alkyl of 1-3 carbon atoms or arylalkyl), --S(O).sub.n --CH.sub.3 or --CH.sub.2 --S(O).sub.n --CH.sub.3 wherein n is zero, one or two;
• X represents hydrogen, lower alkyl, halogen, hydroxy, lower alkoxy, or trifluoromethyl;
• and Y represents --R.sub.2, --OR.sub.2, --NHR.sub.2, or --S(O).sub.n R.sub.2 wherein n is zero, one or two and R.sub.2 is -lower alkylene-vinyl, -lower alkylene-Ar, -lower alkene-Ar, -lower alkene-lower alkylene-Ar, or -lower alkylene-O-Ar, wherein Ar is substituted-phenyl, phenyl, thienyl, or pyridyl wherein there are one or more substituents on the substituted-phenyl independently selected from --H, --Cl, --F, --CH.sub.3, -t-butyl, --CF.sub.3, --OCH.sub.3 and --OH;
• provided that when --R.sub.2 is lower alkylene-O--Ar, Y is not --OR.sub.2, --NHR.sub.2 or --S(O).sub.n R.sub.2.