Compositions
AssigneeBeecham Group Limited
InventorSusan A. Duke
Life of this patent
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Abstract
A toothpaste contains 2% by weight of calcium metasilicate, 0.80% of sodium monofluorophosphate and 44.77% calcium carbonate. The presence of calcium metasilicate in combination with the monofluorophosphate and carbonate increases the fluoride uptake over and above that which is expected from the level of free fluoride present.
Claims10
An anticariogenic oral hygiene composition substantially free of alumina and having improved fluoride release from monofluorophosphate, comprising a source of monofluorophosphate ions, a source of carbonate ions and a source of metasilicate ions, each source being present in an amount such that, in use, an aqueous solution containing from 3.5 to 7.0.times.10.sup.-4 mol.l.sup.-1 dissolved metasilicate ions, from 1 to 2.times.10.sup.-2 mol.l.sup.-1 dissolved monofluorophosphate ions and from 0.5.times.10.sup.-4 to 1.times.10.sup.-3 mol.l.sup.-1 dissolved carbonate ions is produced in the mouth.
An anticariogenic toothpaste, substantially free of alumina, comprising a source of monofluorophosphate ions, a source of carbonate ions and a source of metasilicate ions in an aqueous toothpaste vehicle, in which the ionic concentrations of dissolved monofluorophosphate, carbonate and metasilicate ions are from 4 to 8.times.10.sup.-2 mol.l.sup.-1, from 2.times.10.sup.-4 to 4.times.10.sup.-3 mol.l.sup.-1 and from 1.5 to 3.times.10.sup.-3 mol.l.sup.-1 respectively.
Dependencies are inferred from the claim text.