Ligand compositions and processes for their manufacture and their use in radioimmunoassay

Abstract

A process for preparing a radioactive ligand by reacting an activated ester of the ligand with a primary amine containing a radioactive isotope. An essentially pure composition having the formula: ##STR1## where I is I.sup.125 or non-radioactive I.sup.127. A composition comprising a ligand connected by means of an amide linkage to the above essentially pure composition; and A process for radioimmunoassay using a ligand connected by means of an amide link to an essentially pure composition having the above formula where I is I.sup.125.

Dependencies are inferred from the claim text.