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US 4,357,337 AGranted
Indene derivatives, processes for their preparation, and their use as medicaments
AssigneePharmindustrie
InventorsMarie-Christine Dubroeucq, Claude G. A. Gueremy, Christian L. A. Renault, Gerard R. Le Fur
Life of this patent
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Abstract
Compounds, which can be used as medicaments, of the formula: ##STR1## in which n is 1, 2 ore 3, X is fixed in position 4, 5, 6 or 7 on the cycle ##STR2## and represents a hydrogen atom or a halogen atom or an alkyl, alkoxy or alkylthio group having 1 to 4 carbon atoms, the ##STR3## is fixed in position 2 or 3 on the cycle ##STR4## and the broken line represents a second possible bond, are disclosed for the treatment of states of depression, as analgesics and anti-migraine substances.
Claims15
A compound of the formula:
- ##STR30## in which n is a whole number equal to 1, 2 or 3, X is fixed in position 4, 5, 6 or 7 on the cycle ##STR31## and represents a hydrogen atom, a halogen atom or an alkyl, alkoxy or alkylthio group having 1 to 4 carbon atoms, the ##STR32## is fixed in position 2 or 3 on the cycle ##STR33## and the broken line represents a possible second bond, and its salt of addition with an acid selected from the group consisting of hydrochloric acid, sulfuric acid, phosphoric acid, formic acid, acetic acid, benzenesulfonic acid, paratoluenesulfonic acid, methanesulfonic acid and fumaric acid.
Dependencies are inferred from the claim text.