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US 4,357,334 AGranted
Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
AssigneeEli Lilly and Company
InventorsJean C. Miller, Gerald E. Gutowski
Life of this patent
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Abstract
VLB 3-(2-chloroethyl)carboxamide, the corresponding 4-desacetyl derivative and salts thereof, useful in treatment of neoplasms in pharmaceutical dosage forms.
Claims5
The method of treating neoplasms which comprises administering to a mammal suffering from a vindesine-susceptible neoplasm selected from the group consisting of melanoma, adenocarcinoma, mammary carcinoma, lymphosarcoma, osteogenic sarcoma and leukemia, an antineoplastically-effective amount of a compound of the formula:
- ##STR5## wherein R.sup.1 is OH or acetoxy and pharmaceutically-acceptable acid addition salt thereof.
Dependencies are inferred from the claim text.