Dentifrices with improved soluble fluoride availability

A dentifrice comprising a water soluble monofluorophosphate salt as a source of soluble fluoride in a therapeutically effective anti-caries concentration, an effective abrasive amount of calcium carbonate, from about 0.3 to about 1.0 percent by weight of a dibasic alkali metal phosphate and from about 0.1 to about 1.0 percent by weight of a calcium ion chelator, said dentifrice being devoid of benzyl alcohol.

A dentifrice comprising a water soluble monofluorophosphate salt as a source of soluble fluoride in a therapeutically effective anti-caries concentration, an effective abrasive amount of calcium carbonate, and, as the sole component for increasing retention of said monofluorophosphte as a source of soluble fluoride, from about 0.3 to about 1.0 percent by weight of a dibasic alkali metal phosphate, said dentifrice being devoid of benzyl alcohol.

A dentifrice comprising a water soluble monofluorophosphate salt as a source of soluble fluoride in a therapeutically effective anti-caries concentration, an effective amount of an abrasive consisting of calcium carbonate and from about 0.3 to about 1.0 percent by weight of a dibasic alkali metal phosphate as the sole component for increasing retention of said monofluorophosphate as a source of soluble fluoride, said dentifrice being devoid of benzyl alcohol.

A dentifrice comprising sodium monofluorophosphate as a source of soluble fluoride in a therapeutically effective anti-caries concentration, an effective amount of an abrasive consisting of calcium carbonate and from about 0.3 to about 1.0 percent by weight of a dibasic sodium phosphate as the sole component for increasing retention of said monofluorophosphate as a source of soluble fluoride, said dentifrice being devoid of benzyl alcohol.

A dentifrice comprising a water soluble monofluorophosphate salt as a source of soluble fluoride in a therapeutically effective anti-caries concentration, an effective amount of an abrasive consisting of calcium carbonate, from about 0.1 to about 1.0 percent by weight of a calcium ion chelator and from about 0.3 to about 1.0 percent by weight of a dibasic alkali metal phosphate as the sole component, other than said calcium ion chelator, for increasing retention of said monofluorophosphate as a source of soluble fluoride, said dentifrice being devoid of benzyl alcohol.

A dental cream comprising sodium monofluorophosphate as a source of soluble fluoride in a therapeutically effective anti-caries concentration, an effective amount of an abrasive consisting of calcium carbonate, from about 0.1 to about 1.0 percent by weight of sodium hexametaphosphate and from about 0.3 to about 1.0 percent by weight of dibasic sodium phosphate as the sole component, other than said sodium hexametaphosphate, for increasing retention of said sodium monofluorophosphate as a source of soluble fluoride, said dentifrice being devoid of benzyl alcohol.

A dental cream comprising sodium monofluorophosphate as a source of soluble fluoride in a therapeutically effective anti-caries concentration, an effective amount of an abrasive consisting of calcium carbonate, from about 0.1 to about 1.0 percent by weight of tetrasodium ethylenediamine tetraacetate and from about 0.3 to about 1.0 percent by weight of dibasic sodium phosphate as the sole component, other than said tetrasodium ethylenediamine tetraacetate, for increasing retention of said sodium monofluorophosphate as a source of soluble fluoride, said dentifrice being devoid of benzyl alcohol.

A dental cream consisting essentially of:

• ______________________________________ Ingredients % w/w ______________________________________ Anhydrous dibasic sodium phosphate 1.00 Sodium monofluorophosphate 0.81 Glycerin 12.25 Sodium carboxymethylcellulose 0.92 Xanthan gum 0.38 Sodium saccharin 0.23 Methylparaben 0.06 Propylparaben 0.02 Sorbitol solution (70% w/v) 9.00 Potassium nitrate 5.00 Sodium lauryl sulfate 2.10 Colloidal silica 1.00 Calcium carbonate 30.00 Flavoring 1.35 Distilled water, to make 100.00 ______________________________________

A dental cream consisting essentially of:

• ______________________________________ Ingredients % w/w ______________________________________ Anhydrous dibasic sodium phosphate 1.00 Sodium monofluorophosphate 0.82 Glycerin 12.50 Sodium carboxymethylcellulose 0.20 Xanthan gum 0.55 Sodium saccharin 0.20 Methylparaben 0.06 Propylparaben 0.02 Sorbitol solution (70% w/v) 12.50 Colloidal silica 1.70 Calcium carbonate 35.00 Sodium lauryl sulfate 1.50 Alcohol U.S.P. 0.50 Flavoring 1.40 Distilled water, to make 100.00 ______________________________________